The 5-Second Trick For thr777
The 5-Second Trick For thr777
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This price is calculated by NCBI based upon information from submitters. Examine our guidelines for calculating the critique status. The amount of submissions which add to this review standing is demonstrated in parentheses.
Stars signify the assessment status, or the level of review supporting the submitted (SCV) report. This worth is calculated by NCBI according to facts through the submitter.
ClinVar has an entry for this variant (Variation ID: 574387). Variants that disrupt the consensus splice web page are a comparatively typical reason for aberrant splicing (PMID: 17576681, 9536098). Algorithms created to forecast the result of sequence adjustments on RNA splicing suggest this variant may build or fortify a splice internet site. In summary, the offered evidence is at this time inadequate to find out the part of the variant in condition. Consequently, it's been categorized as a Variant of Unsure Significance. (fewer)
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The worldwide small allele frequency calculated because of the a thousand Genomes Task. The slight allele at this location is indicated in parentheses and will be distinctive with the allele represented by this VCV document.
The aggregate germline classification for this variant, generally for a monogenic or Mendelian problem as in the ACMG/AMP tips, or for response to a drug. This worth is calculated by NCBI based upon information from submitters. Examine our guidelines for calculating the mixture classification.
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The distributing Business for this submitted (SCV) record. This column also includes the SCV accession and Model range, the date this SCV first appeared in ClinVar, and the day that this SCV was final current in ClinVar.
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